Evidation Newsletter: Direct Connection – Translating PGHD into Measures that Matter: Panel Discussion Takeaways

November 30, 2021

Translating PGHD into Measures that Matter: Panel Discussion Takeaways

Incorporating person-generated health data (PGHD) into therapeutic development can give the industry greater understanding of patients’ lived experience and help develop measurements that matter to people. On October 13, 2021, Bray Patrick-Lake, Senior Director of Strategic Partnerships at Evidation, moderated a virtual panel discussion of industry experts who examined how PGHD can revolutionize evidence generation, from preclinical to post approval phases, to ensure we develop the measures and value frameworks that capture changes meaningful to patients.

There is significant groundswell interest and support for such approaches – earlier this year, the US Food and Drug Administration (FDA) hosted a six-hour long webinar that discussed the importance of incorporating patient-centric approaches into regulatory decision-making and the critical role PGHD can play in moving the needle in developing safe and effective medical products that provide meaningful benefit to patients. This paradigm shift is the future of healthcare, as stakeholders agree that we need to measure and pay for what matters most to patients from trials to practice.

READ MORE.

  • AI: Leveraging Wearables and Other Patient-Generated Data in Research | Harvard Medical School Industry Insights

When thinking about opportunities in healthcare for AI, what do you think wearables and other forms of PGHD can bring that traditional medical data cannot? What are some approaches that can help mitigate wearable data that can be noisy when developing an AI system? READ MORE.

  • How Real-World Evidence is Shaping the Future of Healthcare | Forbes

How is real world evidence shaping the future of healthcare? FDA published draft guidance on using real-world evidence to support regulatory decision-making, a critical step towards a larger plan that will ultimately transform healthcare. READ MORE.

  • LumiHealth and Apple Watch Helping Singaporeans Live a Healthier Life | Apple Newsroom

LumiHealth is a first-of-its-kind program as part of Singapore’s Smart Nation initiative, an effort to leverage technology to deliver health benefits. This program has encouraged users to take control of their health and be more active. For example, users have increased their daily exercise minutes by over 39% when compared to the month before joining the program. READ MORE.

Other Good Reads:

FDA AUTHORIZES MARKETING OF VIRTUAL REALITY SYSTEM FOR CHRONIC PAIN REDUCTION | FDA News

DIGITAL MEDICINE SOCIETY TEAMS UP WITH ABBVIE, NOVARTIS, PFIZER, UCB, JANSSEN ON DIGITAL ENDPOINTS INITIATIVE | MobiHealthNews

IT’S TIME FOR INDIVIDUALS – NOT DOCTORS OR COMPANIES – TO OWN THEIR HEALTH DATA | STAT

HEALTH APPS AND WEARABLES HELP RICH PEOPLE THE MOST, STUDY FINDS | The Verge

WEARABLE SENSOR DERIVED DECOMPENSATION INDEX FOR CONTINUOUS REMOTE MONITORING OF COVID-19 DIAGNOSED PATIENTS | npj Digital Medicine

WE’VE ENTERED A NEW ERA OF STREAMING HEALTH CARE. NOW WHAT? | IEEE Spectrum

What We’ve Been Up To:

ANNOUNCEMENTS: At Evidation, we are excited to collaborate with stakeholders across the industry to ensure that sensor data fulfills its promise to improve lives. The Digital Medicine Society Sensor Data Integrations Tour of Duty initiative addresses barriers to improve the effective and efficient use of digital health products at scale. READ MORE.  

THOUGHT LEADERSHIP: Evidation uses data science to find new ways to measure health in everyday life. Our data scientists share how Domino Data Lab and Snowflake helped us deliver production-grade models in as little as eight weeks. READ MORE.

RESEARCH: Engagement is a common challenge across remote app-based studies. Evidation co-authored a paper describing an alternative to the ‘light touch’ digital health remote study that involved a participant centric design for the stress and recovery of frontline COVID-19 healthcare workers. READ MORE.

RESEARCH: Data integration has been key to the development and growth of many technological solutions. Specifically in healthcare, the industry is experiencing a revolution in the use of sensors to collect person-generated health data. Unfortunately, the potential of this data to help improve health outcomes is being held back.

In collaboration with The Digital Medicine Society and other stakeholders, the Sensor Data Integration Tour of Duty addresses challenges and articulates the value, needs and frameworks in incorporating sensor data integration. READ MORE.

RESEARCH: November 14th was World Diabetes Day. To protect vulnerable individuals, specifically those with chronic conditions like Diabetes, it is essential to increase flu vaccination rates. In partnership with Sanofi, Evidation increased flu vaccination rates for individuals with diabetes by 3.1% by leveraging digital health interventions in a decentralized, randomized trial. READ MORE.

HEART HEALTH ON EVIDATION: In our ongoing nationwide Heart Health on Evidation initiative focusing on the lived experience of individuals with heart failure beyond the clinic walls, we found that 22% reported needing help with taking their heart health medications. Medication adherence is critical for chronic disease but involves complex behaviors and components including processes and clinical and patient factors. Knowing that a set of patients will require additional help is an important first step to ensuring better ongoing care and management. READ MORE.

GET TO KNOW YOUR EVIDATION TEAM: Bray Patrick-Lake, Senior Director of Strategic Partnerships at Evidation, recently spoke at the Patient-Centered Outcomes Research’s (PCORI) Virtual Annual Meeting where she discussed enhancing infrastructure to accelerate patient-centered outcomes research. Along with industry leaders like Drs. Robert Califf (Verily and Former FDA Commissioner) and Josie Briggs (PCORI), Bray addressed the importance of measuring what matters to patients and the value of leveraging person-generated health data– data measured outside the clinic walls– to better understand behavior and social determinants of health, to engage underrepresented populations in research, and ultimately drive better health outcomes.