Autoimmune
Understand flares, variability, and treatment response in autoimmune disease
See how disease progression, flare dynamics, treatment experience, and outcomes unfold in the real world, including the symptoms, function, and behavior that claims and clinical data miss.
AT A GLANCE
10×
higher RA prevalence in the top 5% of predicted flare risk
Daily
symptom and flare PROs between visits
At onset
biosamples collected when a flare begins
5.6M
members to find and follow patients
Autoimmune disease is hard to see between visits
Fluctuating symptoms, unpredictable flares, and varied treatment response make real-world disease patterns difficult to characterize.
The gap
What today's data miss
- How flares emerge, evolve, and resolve between visits
- How symptoms and function vary within the same person
- How patients respond to treatment in real-world settings
- What drives disease burden across populations
Open questions
What life sciences teams are asking
- What triggers flares in the real world?
- How do symptoms and functional impact change over time?
- Which biological signals are linked to flare onset and resolution?
- How does real-world variability differ from trial assumptions?
Our approach
A new way to follow progression
- Longitudinal tracking of disease activity in the same people
- High-frequency insight into symptoms, flares, and function
- Biospecimens collected at the time of disease activity
- Treatment response beyond clinical settings
Data for a better understanding of autoimmune conditions
Continuous, direct engagement captures longitudinal, patient-level data across symptoms, behavior, and biology.
Who patients are
- Age, sex, gender identity, race and ethnicity
- Income, education, employment, household
- Insurance, out-of-pocket costs, affordability
- Access barriers: transportation, food, care
What they experience
- Daily flares, pain, fatigue, and disease activity
- Validated instruments (e.g., HAQ-DI, BASDAI)
- Within-patient variability over time
What they do
- Activity, sleep, and heart rate from devices
- Impact on work, participation, and daily function
- Behavior linked to disease activity
Treatment experience
- Medication history, persistence, and adherence
- Switching and patient-reported response
- Experience across therapies
Biological signals
- Biospecimens collected during flares
- Biomarkers linked to symptom dynamics
- Molecular and patient-reported data, integrated
Variation in burden
- Differences in severity and progression
- Variability in treatment response
- Impact on quality of life and function
Clinical data
- Diagnoses, comorbidities, and history (EHR)
- Procedures, specialist visits, treatments
- Healthcare utilization across settings
Real-world outcomes
- Progression and flare patterns over time
- Functional impact and quality of life
- Long-term response and disease control
Trusted by leading life sciences companies:
Real-world insights into autoimmune conditions
Research, webinars, and news from our work with people living with autoimmune disease.
Let's design your next study
Tell us the question you need to answer. Our scientists will show you which cohorts, data types, and study designs can get you there, and how quickly.