PROSPECTIVE Studies

Generate real-world evidence that reflects how health and disease unfold over time

Design and execute prospective, longitudinal studies that capture multimodal data directly from individuals, including symptoms, behavior, and outcomes beyond clinical settings.

Our community Key features our experience

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Design publication-ready real-world studies

Define endpoints aligned to regulatory, payer, or scientific goals
Capture multimodal data directly from individuals over time
Structure studies for publication and external scrutiny

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Start with an engaged, ready-to-study population

Start with deeply characterized populations
Avoid cold-start recruitment and site-based models
Sustain long-term follow-up without site burden

Execute studies quickly and at scale

Rapidly enroll observational cohorts
Maintain strong engagement and data completeness over time
Deliver structured, analysis-ready datasets

The Evidation Community: an ongoing connection to 5M people

*Varies by population, protocol, and length of program; many of our recent programs have seen 90%+ engagement
**Conversion rate for “click to read” offers once offer is seen

Scaled

1M+

Members have participated in research

97%

of U.S. zip codes represented

Characterized

1.3B+

data points collected daily

100+

conditions represented

Engaged

90%

average program engagement*

89%

average response to content seen in app**

How you run real-world studies with Evidation

Design and execute prospective, longitudinal studies that capture multimodal data directly from individuals over time.

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Rapid recruitment from our highly-characterized, responsive health community— meeting specific inclusion/exclusion criteria

A screenshot on a phone showcasing the home screen of the Evidation app; it lists the users points at the top and potential studies to join, the study shown is a card that says "Join our depression study".

A screenshot of a form to be completed with the following fields; electronic signature, signature date, first name, last name, and place of birth.

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Seamless participant experience and onboarding with integrated eConsent and ongoing engagement

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Low-burden, active and passive data capture from participants, aligned to study schedules and real-world behavior

Two phones stacked side by side and slightly on top of eachother. The top phone has a screenshot of a survey that is over 30% completed, the question shown is as follows: "Has a healthcare provider ever referred you to a cardiac rehabilitation program to improve your cardiac health?" The bottom phone showcases a screenshot of the Evidation app and a screen of the connected Apps that have been connected by the user to the Evidation app; the connected app shown is Fitbit with the ready to connect app being Garmin.

A screenshot of the Evidation app, showcasing an option to start a Cardiac Rehab Study and the FAQ of the study. The questions are as follows: Who is running this market research study? What are the option activites? What happens to my data? The answer for this question is shown as follows: We take your privacy and data security very seriously. Your Study Data will be stored securely at all times on limited access, encrypted serves. Only authorized Evidation staff can view your Study Data and external partners will have access to those portions of your study data which they administer. All analyses will be conducted using Coded Study Data (meaning anything that could be used to identify you, such as your name or contact information, will be removed). The last question shown is: What do I get for participating?

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Ongoing participant support with intuitive, easy-to-understand resources and sustained engagement over time

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See how we drive success for our customers:

Identifying and addressing gaps in the patient experience

Myovant uncovered significant unmet needs among individuals with uterine fibroids (UF) in a direct-to-patient 4-month study with 350 women living with UF.

92%

weekly survey completion

85%

daily survey completion

READ

Improving blood pressure in overweight individuals through a digital self-management program

Omada ran a pilot study run managed by Evidation to demonstrate the value of a digital hypertension self-management program by quantifying its impact on blood pressure control. As a result of this study, Omada was able to publish evidence that their app improves blood pressure and medication adherence.

151

individuals with hypertension recruited from the Evidation Community

READ

FluSmart participants receive alerts and nudges to seek care

In partnership with BARDA, Evidation developed and deployed a flu monitoring program, FluSmart, within the Evidation Community to collect rich, longitudinal data and activate high-risk participants into research and care.

200K+

individuals partcipated in FluSmart

90%+

engagement rate

READ

Low-burden, objective assessment of symptoms and disease progression

Evidation partnered with a large pharmaceutical company to conduct a real-world study to create a more complete picture of multiple sclerosis (MS) patients’ experiences by combining data from wearable devices with medical claims and demographics data.

500+

individuals with MS recruited from the Evidation Community

Patients who switched therapies had neuro MRIs

1.5x

more often than those on a single therapy

READ

Increasing treatment rates with co-created patient engagement

Evidation partnered with Sanofi to test and refine content and messaging for a Type 2 diabetes flu vaccine education program.

10K

indviduals recruited from the Evidation Community

Up to

increase in vaccination rates for participants who engaged with customized diabetes campaign vs. those who engaged with generic messaging

READ

Developing an early warning algorithm for individuals at high risk for COVID-19

Evidation conducted a study to demonstrate that person-generated health data, including data from smartphones and wearable devices, has the potential to enable applications ranging from individual-level early warnings or population-level hotspot detection for COVID-19.

800+

individuals recruited from the Evidation Community

>80%

compliance with study activities

READ

Developing an early warning algorithm for individuals at high risk for COVID-19

800+

individuals recruited from the Evidation Community

>80%

compliance with study activities

READ

Rapid enrollment of representative population in COVID-19 research

Evidation partnered with a leading pharmaceutical company to build a patient engagement program focused on COVID-19 that engages a representative population across the United States.

100K

individuals enrolled into reseach program in 5 weeks

90%+

program engagement

1.5K

of those participants recruited into real-world evidence study in 2 weeks

READ

Measuring cognitive impairment with direct-from-patient real-world data

Evidation partnered with Eli Lilly to develop new endpoints and identify digital signals of cognitive impairment through the use of digital and wearable devices, mobile apps, and sleep sensors.

16TB

of multimodal data collected over 12 weeks

1K+

features extracted from participant behaviorgrams

READ

Better Understanding of the Metamorphosis of Pregnancy (BUMP)

Evidation partnered with 4YouandMe to provide a platform to manage data collection, processing, and storage for the BUMP longitudinal feasibility study aimed to gain a deeper understanding of the pre-pregnancy and pregnancy symptom experience using digital tools.

participants targeted for enrollment onto the platform

READ

Developing more successful digital health programs with patient perspectives

Evidation partnered with Sanofi to get data-driven insights to prioritize program features and future development of a connected ecosystem for managing type 2 diabetes (T2D).

114

insulin-dependent adults with T2D recruited from the Evidation community

Recruitment completed in

3 weeks

READ

Demonstrating improved quality of life and activity levels in PNH patients

Evidation partnered with a leading pharmaceutical company to conduct a 32-week direct-to-participant study with paroxysmal nocturnal hemoglobinuria (PNH) patients to characterizes patient experiences while using a C5 inhibitor.

30+

indviduals diagnosed with PNH and taking a specific therapy

>80%

compliance with study activities

READ

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