Research, case studies, and insights

Evidation Launches Temporal Proteomics Platform to Power Autoimmune Research

New AI-enabled data collection platform will drive the development of novel multimodal datasets for biomarker discovery, treatment-response modeling, and foundation models of the immune system.

‍Evidation Shares Insights on Real-World GLP-1 Dosing Behaviors from Over 60,000 Individuals

New insights from Evidation’s cardiometabolic health and weight management cohort, comprised of over 160,000 individuals, show what factors shape real-world dosing decisions.

Evidation Appoints Dr. Ghazanfar Khan as Chief Medical Officer

Evidation appoints Dr. Ghazanfar Khan as Chief Medical Officer. Dr. Khan will advance Evidation’s leadership in real-world data by driving the clinical strategy for direct-to-participant multimodal data collection to fuel AI-powered discovery and evidence generation.

How Evidation is Reshaping Substance Use Disorder (SUD) Research

Evidation is developing a digital experience within the Evidation app, that will engage and educate individuals with SUD while collecting data to support the research and development needs of organizations developing treatments for SUD. 

A New Model for Real-World Data in Weight and Metabolic Health

Evidation’s BODEE-Weight Study recruited nearly 500 adults with BMI ≥25 in three weeks, pairing self-report, wearables, and EHR data to deliver a new interactive model for real-world evidence.

Measuring Real-World Cardiometabolic Health Using Wearable-Derived Data

Evidation's cardiometabolic score, developed through wearable derived data, can reveal subtle shifts in health that precede clinical diagnosis, offering a scalable, privacy-centric way to assess risk, monitor change, and engage individuals.

Evidation Appoints Leslie Oley Wilberforce as CEO

Evidation appoints Leslie Oley Wilberforce as CEO. Wilberforce will lead Evidation’s next phase of growth in interactive real-world data and health research.

GLP-1s: Real-world insights from 10,000 users

Evidation's direct-to-participant connection is reshaping real-world insights into weight management journeys and GLP-1 usage. Explore what's possible with interactive real-world data collected directly from 10,000+ people using GLP-1s.

Leveraging Real-World Data: Insights into Depression from Surveys and Wearables

A continuous, direct connection to an online community of engaged individuals willing to respond to surveys and connect their devices and apps, such as Apple Watches and Fitbits, presents opportunities to capture data longitudinally. These novel, layered datasets help accurately and comprehensively describe the real-world experiences with depression and psycho- and pharmacotherapy.

Evidation appoints Phil Johnson as Chief Commercial Officer

Evidation announces the addition of a new Chief Commercial Officer, Phil Johnson, and board member, Ian Lennox.

A deeper understanding of epilepsy treatment use and need for support services

Jazz Pharmaceuticals contacted our team to help develop and deploy a survey to better understand caregivers’ perspectives on the real-world implications of dependents’ use of Epidiolex and non-FDA-approved cannabinoid products. 

Trialbee and Evidation partner to accelerate and diversify clinical research recruitment

Learn how Evidation and Trialbee's joint offering and shared commitment to inclusion and data transparency drives enrollment outcomes.

Quantifying migraine burden and frequency in day-to-day life

The prevalence and burden of headache disorders in real-world settings is relatively unstudied, leading to underdiagnosis and condition management challenges.

Rock Health shares findings from weight care survey with Evidation

Evidation helped Rock Health conduct surveys that investigated experience and perceptions of a variety of weight care solutions. Read key highlights here.

Behavioral Engagement and Activation Model Study (BEAMS)

Evidation and Sanofi partnered to look at Type 2 Diabetes patients with and without digital health technology (DHT) use to understand who might require more tailored support to adopt DHTs.

John D Piette, Keni C S Lee, Hayden B Bosworth, Diana Isaacs, Christian J Cerrada, Raghu Kainkaryam, Jan Liska, Felix Lee, Adee Kennedy, David Kerr

Frost & Sullivan awards Evidation for its direct-to-participant real world data solutions

Evidation’s consumer app and research platform have been recognized by Frost & Sullivan for the value they provide to life science and healthcare organizations and individuals in everyday life

Evidation launches MigraineSmart on the Evidation app

Evidation has officially launched MigraineSmart, a health engagement experience and symptom tracking program on the Evidation app that harnesses different forms of data to help individuals better understand and manage their migraines.

RWD’s value in accelerating autoimmune disease diagnosis

Watch Evidation's webinar to learn how real-world data can improve early detection, enhance AI analysis, and support healthcare discussions in autoimmune disease diagnosis.

Why do people participate in research? The answer could be the key to long-term engagement.

Long-term engagement of research participants benefits from aligning study activities with intrinsic and extrinsic motivators for participation. Read about how this can be achieved in the blog post.

Evidation shares real world data on GLP-1 use and social determinants of health at ISPOR 2024

Evidation will be presenting recent research findings in two accepted abstracts at this year’s International Society for Pharmacoeconomics and Outcomes Research (ISPOR) conference in Atlanta.

Participant-first recruitment: Building relationships, trust, and seamless experiences

Evidation's clinical research experts sit down for a chat about overcoming barriers to both recruitment and enrollment.

Faster results, better outcomes: How person-centered trial design improves clinical research

The growing emphasis on person-centric research in the clinical trial industry stems from a desire to develop and market products and interventions that actually meet individuals' needs.

Characterizing life events through self-report and wearable data

Healthcare industry stakeholders increasingly expect healthcare data to demonstrate the real-world value of new interventions to support approval, reimbursement, and prescribing decisions. Yet, this value is challenging to demonstrate with today’s siloed data sources.

5 reasons why the right people aren't joining your trials

In this webinar, our Senior Director of Product and Portfolio Strategy, Abby Levine, discusses the survey results from Evidation’s highly engaged, online member community and insights based on Evidation’s 10+ years of experience in research recruitment, revealing several common reasons why people have not participated in clinical trials.

Diverse voices, better care: The role of PROs in advancing health equity

In this webinar, industry experts share practical learnings in how patient-reported outcomes can help with challenges in understanding, diagnosing, and treating various medical conditions in a way that advances health equity.

5 keys to high participant engagement in real-world research

Meeting healthcare's evolving needs: Harnessing digital platforms for real-world data, addressing engagement challenges in ongoing participant research.

Patient and physician perspectives on the use of a connected ecosystem for diabetes management: International cross-sectional observational study

Evidation and Sanofi partnered to understand which type 2 diabetes patients are more likely to participate in and benefit from connected ecosystem programs.

Elizabeth Benito-Garcia; Julio Vega; Eric J Daza; Wei-Nchih Lee; Adee Kennedy; Jean-Marc Chantelot

Uncovering the unseen in patients living with paroxysmal nocturnal hemoglobinuria (PNH): Results from the REVEAL study

Uncovering opportunities to improve workplace equity with longitudinal RWD

Evidation selected by Our Future Health as participant platform for UK’s largest health research program

Evidation’s digital health engagement and measurement platform has been selected by Our Future Health to power the multi-year, longitudinal research program for up to five million participants across the UK.

From in-person trials to DCTs and back again: Why has implementation of remote trials been so challenging?

Evidation's Senior Director of Clinical Operations, Joyce Nortey, sheds light on some of the challenges and best practices for implementing decentralized clinical trials.

“Wearables mean the sky’s the limit”: A conversation on USC & Evidation’s partnership on the Understanding America Study

Evidation and USC sit down to discuss the goals of the Understanding America Study and how its new wearables integration with Evidation can help achieve them.

5 industry insights to enhance real-world evidence strategies

Unpacking the lived experience: How loneliness can affect our health

Evidation analyzed permissioned data from approximately 95,000 respondents to see if a combination of self-reported and wearable data could more accurately highlight novel trends and associations between loneliness and overall health.

Closing neurology’s data gaps: Integrating wearables and decentralized, at-home studies to transform research and care

In this webinar, industry experts share practical learnings in how they’re creating a more robust picture of their patients.

BARDA expands partnership with Evidation to validate and improve machine learning models for early detection of influenza-like illness using wearables

Evidation announced that BARDA has awarded the company a contract to fund the 2023 Influenza-like Illness (ILI) Detect & Protect Studies.

Evidation partners with USC on the Understanding America Study to characterize healthy aging using wearables and real-world data

Evidation announced a partnership with USC’s Dornsife Center for Economic and Social Research to incorporate wearable device data into the landmark Understanding America Study.

Understanding the neurological patient experience

Download Evidation's executive brief: Understanding the neurological patient experience

Filling gaps in real-world data

Download Evidation's white paper: Filling gaps in real-world data

3 ways Evidation can accelerate your trial recruitment

The FluSmart experience

By using a predictive algorithm informed by participant steps, heart rate, and sleep, Evidation's FluSmart can activate the right person at the right time, which can help produce better health outcomes, faster. View the infographic to learn more.

Quickly connect the right participants to your trial

Evidation can improve the speed of recruitment and the quality of potential trial participants by identifying, engaging with, and providing a point-of-trial entry for eligible members from within the Evidation Community. View the infographic for more information.

Association of digital measures and self-reported fatigue

Evidation contributed to research that looked at whether or not multimodal digital data can be used to quantify fatigue in both healthy individuals and individuals with chronic inflammatory rheumatic disease.

The patient-perceived burden of pain in uterine fibroids: Results from a prospective real-world evidence study

Read this case study to learn how Evidation was able to provide a lens into the quality of life of women living with uterine fibroids.

Measuring quality of life and patient experience with longitudinal digital measures

Read this case study to learn how Evidation used digital measures to create an objective view of how skin conditions impact patients and caregivers.

We can do better, for more people

Hear from CEO Christine Lemke about how Evidation leverages permissioned data to tell individuals' health stories, taking the burden off the individuals themselves.

Myovant Sciences and Evidation survey explores lived experiences and unseen burdens of women and individuals with endometriosis and uterine fibroids

Read findings from Evidation and Myovant surrounding the impact of endometriosis and/or uterine fibroids on work, school, and activities of daily living.

Myovant Sciences and Evidation announce survey results of unseen burdens at work and school of individuals with endometriosis and/or uterine fibroids

Evidation and Myovant uncover staggering findings around the impact of endometriosis and uterine fibroids on quality of life.

Supporting conversations at the point of care with personalized health insights

Read this case study to learn about how Evidation enables individuals to better understand and act on their heart health outside of clinical settings.

Increasing treatment rates with co-created patient engagement

Read this case study to learn how Evidation increased vaccination rates through customized messages and content.

pharmaphorum Podcast

Hear more about Evidation's founding story and platform from our Executive Chair of the Board, Deb Kilpatrick in this episode of the pharmaphorum podcast.

Supporting whole person care: the power of longitudinal patient-provided real-world data

Read key takeaways from Evidation's webinar, "Using longitudinal RWD to boost activation along the patient journey," featuring speakers from Evidation, Veterans Affairs, and Myovant Sciences.

Machine learning COVID-19 detection from wearables

Evidation research looks into which criteria must be met before a study can claim reasonable COVID-19 detection performance using data from wearable devices.

Bret Nestor, Jaryd Hunter, Raghu Kainkaryam, Erik Drysdale, Jeffrey B Inglis, Allison Shapiro, Sujay Nagaraj, Marzyeh Ghassemi, Luca Foschini, Anna Goldenberg

Characterization of influenza-like Illness burden using commercial wearable sensor data and patient-reported outcomes: Mixed methods cohort study

Evidation research aimed to characterize the burden of influenza-like illness using commercial wearable sensor data and investigate the extent to which these data correlate with self-reported illness severity and duration.

Victoria Hunter, Allison Shapiro, Devika Chawla, Faye Drawnel, Ernesto Ramirez, Elizabeth Phillips, Sara Tadesse-Bell, Luca Foschini, Vincent Ukachukwu

Using longitudinal RWD to boost activation along the patient journey

People now play a more active role in their own health—but too often don’t know about relevant care and resources.

Precision recruitment for high-risk participants in a COVID-19 cohort study

Evidation describes an approach for reducing recruiting time and resources in a COVID-19 study by targeting recruitment to high-risk individuals.

Mezlini A, Caddigan E, Shapiro A, Ramirez E, Kondow-McConaghy H, Yang J, DeMarco K, Naraghi-Arani P, Foschini L

Evidation enables rapid recruitment and enrollment for Veterans heart health program

Evidation, alongside key partners, will present findings from a Veterans heart health program at the American College of Cardiology's Annual Scientific Session & Expo.

AWS Health Innovation Podcast

Hear more about Evidation's founding story from Co-Founder and Chief Technology Officer, Alessio Signorini, in this episode of the AWS Health Innovation Podcast.

American Life in Realtime: A benchmark registry of health data for equitable precision health

ALiR, funded by a grant from the NIH, is a first-of-its-kind, publicly available benchmark registry and research infrastructure for person-generated health data collected from smartphones and wearables, made possible by Evidation.

Ritika R. Chaturvedi, Marco Angrisani, Wendy M. Troxel, Tania Gutsche, Eva Ortega, Monika Jain, Adrien Boch & Arie Kapteyn

Evidation and Duke Big Ideas Lab partner to boost participation and increase equity in digital health research

Evidation and Duke Big Ideas Lab announce a partnership with the goal of increasing diversity and representation in digital health studies

Predictors of seeking care for influenza-like illness in a novel digital study

Evidation conducted a study that used person-generated health data (PGHD) to identify factors associated with seeking care for ILI.

Devika Chawla, Alejandra Benitez, Hao Xu, Victoria Whitehill, Sara Tadesse-Bell, Allison Shapiro, Ernesto Ramirez, Kelly Scherer, Luca Foschini, Faye Drawnel, Barry Clinch, Marco Prunotto, Vincent Ukachukwu

Evidation launches FluSmart, a direct-to-person digital flu monitoring program, to better understand flu in everyday life

Evidation announces the launch of FluSmart, a direct-to-person digital flu monitoring program hosted on the Evidation platform.

Individuals diagnosed with breast cancer or in remission self-report QoL

Person-generated health data (PGHD) shows promise in detecting cognitive impairment & informing therapies.

COVID-19 real-world evidence primer

Evidation contributed to this online resource consisting of seven chapters that cover types of RWD, methods in RWE generation, examples of RWE studies, and more.

Amy Cavet; Claire Cravero, MPH; Aaron Galaznik, MD; Bray Patrick-Lake, MFS; Aniketh Talwai

The case for multimodal data capture: Deeper insights and increased prediction accuracy

Evidation participated in an IEEE EMBS workshop that explored how machine learning can convert data into measures for both disease detection and overall quality of life. The key takeaways are presented in this article.

What possibly affects nighttime heart rate? Conclusions from n-of-1 observational data

Evidation's Lead Biostatistician, Eric J. Daza, worked with the Quality of Life Technology Lab to conduct an n-of-1 study using the MoTR method to evaluate the suggested effects of daily stressors on nighttime heart rate, sleep time, and physical activity in an individualized way.

Igor Matias, Eric J. Daza, Katarzyna Wac

Model-Twin Randomization (MoTR): A Monte Carlo method for estimating the within-individual average treatment effect using wearable sensors

In this academic preprint, the model twin randomization (MoTR; "motor") method for analyzing possible causes and effects an individual's intensive longitudinal data is introduced.

Eric J. Daza, Logan Schneider

How can we optimise health technology assessment and reimbursement decisions to accelerate access to new cardiovascular medicines?

This paper builds on discussions among clinical trialists, industry representatives, regulators, and patients, which took place at the 17th Global Cardiovascular Clinical Trialists (CVCT) Forum in December 2020.

Martin R. Cowie, Biykem Bozkurt, Javed Butler, Andrew Briggs, Maria Kubin, Adrian Jonas, Amanda I. Adler, Bray Patrick-Lake, Faiez Zannad

Boston University, Evidation publish study on voice as a digital marker in detection of Alzheimer’s disease

Evidation researchers, alongside researchers at Boston University School of Medicine, have announced the publication of study results that examine the use of voice recordings and transcripts as potential diagnostic tools for Alzheimer's Disease.

Cognitive digital biomarkers for automated transcription of spoken language

Evidation research reveals that the use of voice-based digital biomarkers might be a valuable tool in detecting and differentiating mild cognitive impairment and dementia

N. Tavabi, D. Stück, A. Signorini, C. Karjadi, T. Al Hanai, M. Sandoval, C. Lemke, J. Glass, S. Hardy, M. Lavallee, B. Wasserman, T. F. A. Ang, C. M. Nowak, R. Kainkaryam, L. Foschini & Rhoda Au

Influence of digital intervention messaging on influenza vaccination rates among adults with cardiovascular disease in the United States: A decentralized randomized clinical trial

Evidation research reveals that a personalized, evidence-based digital intervention could be effective in increasing vaccination rates in a population of high-risk people with cardiovascular disease.

Nell J. Marshall, Jennifer L. Lee, Jessica Schroeder, Wei-Nchih Lee, Jermyn See, Mohammad Madjid, Mrudula R. Munagala, John D. Piette, Litjen Tan, Orly Vardeny, Michael Greenberg, Jan Liska, Monica Mercer, Sandrine Samson

Using digital health technologies to transform community health and health equity

Evidation responded to an RFI from the White House Office of Science and Technology Policy (OSTP) to provide input on how digital health tools can transform community health and health equity.

The n-of-1 that counts

Elvira’s story shows us the amazing potential for n-of-1 trials and SCEDs to help each of us figure out exactly what’s going on in our own lives. They can help us use our own PGHD to determine what actually influences our own health each and every day, regardless of how those same triggers harm—or may even help—others.

Eric J. Daza

Measuring health-related quality of life with multimodal data: Viewpoint

Evidation contributed to a summary of how multimodal technologies capable of measuring several modalities simultaneously provide value to stakeholders.

Ieuan Clay, Francesca Cormack, Szymon Fedor, Luca Foschini, Giovanni Gentile, Chris van Hoof, Priya Kumar, Florian Lipsmeier, Akane Sano, Benjamin Smarr, Benjamin Vandendriessche, Valeria De Luca

Evidation partners with other industry leaders to launch resources to drive inclusion in digital health measurement

Evidation and other members of the Digital Health Measurement Collaborative Community (DATAcc) announced a new set of open-access resources to guide inclusivity in digital health measurement products from development to deployment.

Next generation patient engagement & enriched insights

Evidation has written a white paper that takes a closer look at the challenges of PGHD, its value to clinical decision makers, and how to contextualize it to optimize its value.

COPD — Determine high-impact clinical markers with person-generated health data (PGHD)

Combining activity and behavioral-related data can predict exacerbations in Chronic Obstructive Pulmonary Disease (COPD) patients

Estimating the burden of influenza-like illness on daily activity at the population scale using commercial wearable sensors

Evidation research reveals that most of the burden of influenza-like illness is invisible to health care and public health reporting systems.

Aziz Mezlini, Allison Shapiro, Eric J. Daza, Eamon Caddigan, Ernesto Ramirez, Tim Althoff, Luca Foschini

How do we make patient centricity a reality?

For years, the subject of fostering direct connections with patients has been highlighted by notable figures across the healthcare and life sciences industries as a key feature to be explored in future strategies.

Rheumatoid Arthritis — The pandemic’s impact on Rx adherence & access to care

Non-adherence to medication & unwillingness to visit health facilities soar due to COVID-19.

Asthma — PGHD delivers a roadmap to optimal treatment

Person-generated health data (PGHD) allows users to identify and segment patients based on real world behaviors and disease impact.

Creating competitive advantage: Privacy and security by design in mHealth and digital health products

Evidation's Head of Privacy looks at the increased need for cybersecurity and privacy protection amidst the boom in digital health advancements.

Alea Garbagnati, Esq. and Lauren Wu, Esq.

Making equitable health a reality

Building an equitable and inclusive space in the healthcare ecosystem where everyone - research and health program participants, partners, and employees - can belong and feel valued is a foundational pillar of Evidation’s mission. National Minority Health Month provides an excellent opportunity for us to reflect on ways health and racial equity can be improved.

Digital Medicine Society, Evidation, and industry partners launch toolkit to support reimbursement for new drugs developed using digital endpoints

Today, the Digital Medicine Society (DiMe), in partnership with Evidation, Anthem, Biogen, Eli Lilly, Janssen, Merck, Pfizer, and Savvy Co-op, announced the public launch of the 3Ps of Digital Endpoint Value (3Ps), a toolkit of resources created to facilitate the inclusion of digital endpoints as evidence for payers in reimbursement decisions for new drugs.

Multiple Sclerosis — Wearable data can assess MS patients’ disease activity

Evaluating minute-level data obtained from passive trackers has the potential to help in determining patients’ disease state and progression.

Dyslipidemia / High Cholesterol: PGHD delivers valuable insights for cholesterol management

Person-generated health data (PGHD) can lead to deeper understanding and help inform better treatment options.